Ozone in Dental Therapy
DOI:
https://doi.org/10.12974/2311-8695.2016.04.01.3Keywords:
Oxidant, antimicrobial, immune modulator, caries, osteonecrosis, dental problems.Abstract
A literature search was performed using MEDLINE (PubMed) and other electronic basis from 1991 to 2014. Search included books and journals based on the systematic and critical reviews, in vitro and in vivo clinical studies on Ozone therapy in dentistry. Ozone has been shown as powerful oxidizing agent capable of interacting as metabolic, immune modulator as well as an antimicrobial agent. It has been used to stimulate remineralisation of recent caries-affected teeth, as a preventive therapy in caries, root caries, intra-canal irrigants in endodontic treatment, treatment of alveolitis, avascular osteonecrosis of the jaw, herpes virus infection, to inhibits plaque formation, an adjuvant in periodontal surgical and maintenance phase and to disinfect implant surface and treat peri-implantitis and in water line to disinfect water.
References
Sameer Makkar and Monica Makkar. Ozone –treating dental infections. Indian J Stomatol 2011; 2(4): 256-9.
Nogales CG, Ferrari PA, Kantorovich EO and Lage-Marques JL. Ozone Therapy in Medicine and Dentistry. J Contemp Dent Pract 2008; 4(9): 75-84.
Ekstrand K. Ozone therapy for the treatment of dental caries. Danish Center for Evaluation and Health Technology Assessment health technology alert 2005 March; 4:1
[online].
[cited2010 January 13];
screens].
BikashPattanaik, Dinesh Jetwa, SeemaPattanaik, Sachin Manglekar and Dinesh N. Ozone therapy in Dentistry: A literature review. J of Interdisciplinary Dentistry 2011; 1(2): 87-92. http://dx.doi.org/10.4103/2229-5194.85024
Health technology assessment report. Ozone therapy
[online] December 2005
[cited 2010 January 13]. Available from: URL:http://www.moh.gov.my
Garg R and Tandon S. Ozone: A new face of dentistry. The Internet Journal of Dental Science 2009; 7: 2.
Seidler V, Linetskiy I, Hubalkova H, Stankova H, Smucler R and Mazanek J. Ozone and its usage in General Medicine and Dentistry. Prague Medical Report 2008; 109: 5-13.
Mollica P and Harris R. Integrating oxygen/ ozone therapy into your practice.
[Online].
[Cited 2010 January 13];
screens]. Available from: URL: http://www. Toxin free smile. Dom/ images/ozone integrating 20% oxygen ozone 20% therapy your practice. Pdf.
Gupta G and Mansi B. Ozone therapy in Periodontics. J of Medicine and Life 2012; 5(1): 56-63.
Brauner A. A clinical investigation of the therapeutic success of ozonized water in treating gingivitis and periodontitis. Zahnarztl Praxis 1991; 2: 48-50.
Johanson E, Claeson R and VanDijken JW. Antibacterial effect of ozone on cariogenic bacterial species. J Dent 2009; 37: 449-453. http://dx.doi.org/10.1016/j.jdent.2009.02.004
Johnson RD. Oxygen/ ozone therapy. Alternative approach to dental health.
[Online].
[Cited 2010 January 13]. Available from: URL: Dr.runarjohnson. Com/ozone. Htm
Seaverson K, Tschetter D and Kaur T. Patient guide to oxygen/ozone therapy. Health centered cosmetic dentistry.
[Online].
[Cited 2010 January 13]. Available from: URL:http://www.toothbythelake.net/ozone_therapy.html
Huth KC, Sauge lB, Jakob FM, Cappello C, Quirling M, Paschos E, et al. Effect of aqueous ozone on the NF-kappa B system. J Dent Res 2007; 86(5): 451-456. http://dx.doi.org/10.1177/154405910708600512
Teresa B, Wolanska E, Cieszko- Buk M, Orlowski M and Chalas R. Practical use of ozone in Dentistry-comments. AnnalesUniversitatis Maria Curie- SklodowskaLubin- Polonia.2008;vol LXIII, N 1,28 SECT10 D.
Dr. George P. Gum and Bone Regeneration Procedures. Australian Institute of Implant Dentistry
[online].
[Cited 2010 january 13];
screen]. Available from: URL:http://www.implantdentistry.com.au/html/gumbone.html# wrap.
Ozone Therapy Oxygen Therapies. Applied ozone systems.
[Online].
[Cited 2010 January 13]. Available from URL:http://www.appliedozone.com/medical.html
Huth KC, Jacob FM, Saugel B, Cappello C, Paschos E, Hollweck R, et al. Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci 2006; 114: 435-440. http://dx.doi.org/10.1111/j.1600-0722.2006.00390.x
Nagarakanti S and Athuluru D. Ozone a new revolution in Dentistry. Dentistry 2011; 2(12): WMC002685.
Abu-Naba’a L. Management of primary occlusal pit and fissure caries using ozone. Belfast, UK: Queen’s University 2003.
Huth KC, Paschos E, Brand K and Hickel R. Effect of ozone on noncavitated fissure carious lesions in permanent molars: a controlled prospective clinical study. Am J Dent 2005; 18: 223-228.
Dähnhardt JE, Gygax M, Martignoni B, Suter P and Lussi A. Treating sensitive cervical areas with ozone. a prospective controlled clinical trial. Am J Dent 2008; 21: 74-76.
Zaura E, Buijs MJ and Ten Cate JM. Effects of ozone and sodium hypochlorite on caries-like lesions in dentin. Caries Res 2007; 41: 489-492. http://dx.doi.org/10.1159/000109086
Johanson E, Claeson R and VanDijken JW. Antibacterial effect of ozone on cariogenic bacterial species. J Dent 2009; 37: 449-453. http://dx.doi.org/10.1016/j.jdent.2009.02.004
Baysan A and Lynch E. Effect of ozone on the oral microbiota and clinical severity of primary root caries. Am J Dent 2004; 17: 56-60.
Holmes J. Clinical reversal of root caries using ozone, doubleblind, randomised, controlled 18-month trial. Gerodontology 2003; 20: 106-114. http://dx.doi.org/10.1111/j.1741-2358.2003.00106.x
Nagayoshi M, Kitamura C, Fukuizumi T, Nishihara T and Terashita M. Antimicrobial effect of ozonated water on bacteria invading dentinal tubules. J Endod 2004; 30: 778-781. http://dx.doi.org/10.1097/00004770-200411000-00007
Azarpazhooh A, Limeback H, Lawrence HP and Fillery ED. Evaluating the effect of an ozone delivery system on the reversal of dentin hypersensitivity: a randomized, double blinded clinical trial. J Endod 2009; 35: 1-9. http://dx.doi.org/10.1016/j.joen.2008.10.001
SiqueiraJr JF, Rocas IN, Cardoso CC, Macedo SB and Lopes HP. Antibacterial effects of a new medicament- the ozonized oil compared to calcium hydroxide pastes. Rev Bras Odontol 2000; 57: 252-256.
Silveira AM, Lopes HP, Siqueira JF Jr, Macedo SB and Consolaro A. Periradicular repair after two-visit endodontic treatment using two different intracanal medications compared to single-visit endodontic treatment. Braz Dent J 2007; 18: 299-304. http://dx.doi.org/10.1590/S0103-64402007000400005
Virtej A, MacKenzie CR, Raab WH, Pfeffer K and Barthel CR. Determination of the performance of various root canal disinfection methods after in situ carriage. J Endod 2007; 33: 926-929. http://dx.doi.org/10.1016/j.joen.2006.11.025
Cardoso MG, de Oliveira LD, Koga-Ito CY and Jorge AO. Effectiveness of ozonated water on Candida albicans, Enterococcus faecalis and endotoxins in root canals Oral Surg Oral Med Oral Pathol Oral RadiolEndod 2008; 105: 85-91. http://dx.doi.org/10.1016/j.tripleo.2007.10.006
Bezrukova IV, Petrukhina NB and Voinov PA. Experience in medical ozone use for root canal treatment. Stomatologiia (Mosk) 2005; 84: 20-22.
Celiberti P, Pazera P and Lussi A. The impact of ozone treatment on enamel physical properties. AmJ Dent 2006; 19: 67-72.
Polydorou OPK and Hahn P. Antibacterial effect of an ozone device and its comparison with two dentin-bonding systems. Eur J Oral Sci 2006; 114: 349-353. http://dx.doi.org/10.1111/j.1600-0722.2006.00363.x
Schmidlin PR, Zimmermann J and Bindl A. Effect of ozone on enamel and dentin bond strength. J Adhes Dent 2005; 7: 29-32.
Tessier J, Rodriguez PN, Lifshitz F, Friedman SM and Lanata EJ. The use of ozone to lighten teeth. An experimental study. Acta OdontolLatinoam 2010; 23(2): 84-89.
Knight GM, McIntyre JM, Craig GG, Mulyani and Zilm PS. The inability of Streptococcus mutans and Lactobacillus acidophilus to form a biofilm in vitro on dentine pretreated with ozone. Aust Dent J 2008; 53: 349-353. http://dx.doi.org/10.1111/j.1834-7819.2008.00077.x
Muller P, Guggenheim B and Schmidlin PR. Efficacy of gasiform ozone and photodynamic therapy on the multispecies oral biofilm in vitro. Eur J OralSci 2007; 115: 77-80. http://dx.doi.org/10.1111/j.1600-0722.2007.00418.x
Srikanth A, Sathish M and Sri Harsha AV. Application of ozone in the treatment of periodontal disease. J Pharm Bioall Sci 2013; 5 Suppl S1: 89-94. http://dx.doi.org/10.4103/0975-7406.113304
Kshitish D and Laxman VK. The use of ozonated water and 0.2% chlorhexidine in the treatment of periodontitis patients: a clinical and microbiologic study. Indian J Dent Res 2010; 21: 341-348. http://dx.doi.org/10.4103/0970-9290.70796
Ramzy MI, GomaaHE, Mostafa MI and Zaki BM. Management of Aggressive Periodontitis using ozonized water. Egypt Med J N R C 2005; 6(1): 229-245.
SigrunEick, MariusTigan M and Anton Sculean A. Effect of ozone on periodontopathogenic species- an in vitro study.Clin Oral Investigative 2012; 16: 537-544. http://dx.doi.org/10.1007/s00784-011-0515-1
Estrela C, Estrela CR, DecurcioDde A, Silva JA and Bammann L. Antimicrobial potential of ozone in an ultrasonic cleaning system against Staphylococcus aureus. Braz Dent J 2006; 17: 134-8. http://dx.doi.org/10.1590/S0103-64402006000200010
Polydorou O, Halili A, Wittmer A, Pelz K and Hahn P. The antibacterial effect of gas ozone after 2 months of in vitro evaluation. Clin Oral Investig 2011; 16(2): 545-550. http://dx.doi.org/10.1007/s00784-011-0524-0
Vescovi P and Nammour S. Bisphosphonate-related Osteonecrosis of the Jaw (BRONJ) therapy. A critical review. Minerva Stomatol 2010; 59: 181-203.
Agapov VS, Shulakov VV and Fomchenkov NA. Ozone therapy of chronic mandibular osteomyelitis. Stomatologiia (Mosk) 2001; 80: 14-7.
Petrucci MT, Gallucci C, Agrillo, Mustazza MA and Robin FO. Role of ozone therapy in the treatment of osteonecrosis of the jaws in multiple myeloma patients. Haematologica 2007; 92(9): 1289-1290. http://dx.doi.org/10.3324/haematol.11096
Agrillo A, Sassano P, Rinna C, Priore P and Iannetti G. Ozone therapy in extractive surgery on patients treated with bisphosphonates. J Craniofac Surg 2007; 18: 1068-1070. http://dx.doi.org/10.1097/SCS.0b013e3181572609
Agrillo A, Petrucci MT, Tedaldi M, Mustazza MC, Marino SM, Gallucci C, et al. New therapeutic protocol in the treatment of avascular necrosis of the jaws. J Craniofac Surg 2006; 17: 1080-1083. http://dx.doi.org/10.1097/01.scs.0000249350.59096.d0
Karapetian VE, Lowden E and Zöller JE. The Use of Ozone in Periimplantitis-Treatment - Das Deutsche Zahnärzteblatt 2007; 116: 214-218.
Filippi A. The influence of ozonised water on the epithelial wound healing process in the oral cavity. Deutsche ZahnärztlicheZeitschrift 1997; 56: 104-108.
Ebensberger U, Pohl Y and Filippi A. PCNA-expression of cementoblasts and fibroblasts on the root surface after extraoral rinsing for decontamination. Dental Traumatology 2002; 18: 262-266. http://dx.doi.org/10.1034/j.1600-9657.2002.00087.x
Huth KC, Jacob FM, Saugel B, Cappello C, Paschos E, Hollweck R, et al. Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci 2006; 114: 435-440. http://dx.doi.org/10.1111/j.1600-0722.2006.00390.x
Bialoszewski, D, Pietruczuk-Padzik A, Kalicinska A, Bocian E, Czajkowska, Bukowska B and Tyski S. Activity of ozonated water and ozone against Staphylococcus aureus and Pseudomonas aeruginosa biofilms. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2011; 17(11): BR339-BR344. http://dx.doi.org/10.12659/MSM.882044
Arita M, Nagayoshi M, Fukuizumi T, Okinaga T, Masumi S, Morikawa M, et al. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. OralMicrobiolImmunol 2005; 20: 206-210. http://dx.doi.org/10.1111/j.1399-302x.2005.00213.x
Murakami H, Mizuguchi M, Hattori M, Ito Y, Kawai T and Hasegawa J. Effect of denture cleaner using ozone against methicillin resistant Staphylococcus aureus and E. coli T1 phage. Dent Mater 2002; 21: 53-60. http://dx.doi.org/10.4012/dmj.21.53
Oizumi M, Suzuki T, Uchida M, Furuya J and Okamoto Y. In vitro testing of a denture cleaning method using ozone. J Med Dent Sci 1998; 45: 135-139.
Walker JT, Bradshaw DJ, Fulford MR and Marsh PD. Microbiological evaluation of a range of disinfectant products to control mixed-species biofilm contamination in a laboratory model of a dental unit water system. Appl Environ Microbiol 2003; 69: 3327-3332. http://dx.doi.org/10.1128/AEM.69.6.3327-3332.2003
Wafaa Hikal, Basma Zaki and Hany Sabry. Evaluation of Ozone Application in Dental Unit Water Lines Contaminated with Pathogenic Acanthamoeba. Iran J Parasitol 2015; 10(3): 410-419.
Sebastian G Ciancio. Biological therapies in Dentistry. A Bimonthly newsletter for dental professionals 2005; 21(1): S2-5.
Elvis AM and Ekta JS. Ozone therapy: A clinical review. J Nat Sci Biol Med 2011; 2(1): 66-70. http://dx.doi.org/10.4103/0976-9668.82319
Baysan A, Wiley R and Lynch E. Antimicrobial effect of a novel ozone generating device on micro organisms associated with primary root carious lesions in vitro. Caries Res 2000; 34: 498-501. http://dx.doi.org/10.1159/000016630
Saini R. Ozone therapy in dentistry: A strategic review. Journal of Natural Science, Biology, and Medicine 2011; 2(2): 151-153. http://dx.doi.org/10.4103/0976-9668.92318
Pattanaik B, Jetwa D, Pattanaik S, Manglekar S, Naitam DN and Dani A. Ozone therapy in dentistry: A literature review. J Interdiscip Dentistry 2011; 1: 87-92. http://dx.doi.org/10.4103/2229-5194.85024