Attention Deficit Hyperactivity Disorder in Adulthood: A Comprehensive

Authors

  • Ilaria Bertolucci Miller Institute of Behavioral and Cognitive Psychotherapy, Florence, Italy

DOI:

https://doi.org/10.12974/2313-1047.2025.12.03

Keywords:

Adulthood ADHD, Adults, Attention hyperactivity disorder, DSM-5, Psychological interventions, Psychiatric comorbidities, Medical comorbidities, Attention, Impulsivity, restlessness, Hyperactivity

Abstract

Attention-deficit hyperactivity disorder (ADHD) in adults is a neurodevelopmental disorder marked by persistent symptoms, including inattention, emotional dysregulation, impulsivity, and restlessness. In adults, ADHD can result in unstable interpersonal relationships, impaired academic or occupational performance, and diminished self-esteem, thereby adversely affecting quality of life. This paper provides an overview of the literature on the etiology, diagnosis, and treatment of adult ADHD. Diagnosis is frequently delayed until adulthood or misunderstood. Assessment challenges include subtler symptom presentation compared to children and diagnostic overshadowing by medical and psychiatric comorbidities. Pharmacotherapy is the first-line treatment for adults with ADHD. Cognitive Behavioral Therapy is the most widely used psychological intervention.

References

Adamis, D., Kasianenko, D., Usman, M., Saleem, F., Wrigley, M., Gavin, B., & McNicholas, F. (2023). Prevalence of Personality Disorders in Adults With Attention Deficit Hyperactivity Disorder (ADHD). Journal of Attention Disorders, 27(7), 658-668. https://doi.org/10.1177/10870547231161531

Adamou, M., Arif, M., Asherson, P., Aw, T. C., Bolea, B., Coghill, D., ... & Young, S. (2013). Occupational issues of adults with ADHD. BMC psychiatry, 13(1), 59.https://doi.org/10.1186/1471-244X-13-59

Agarwal, R., Goldenberg, M., Perry, R., & Ishak, W. W. (2012). The quality of life of adults with attention deficit hyperactivity disorder: a systematic review. Innovations in clinical neuroscience, 9(5-6), 10.

American Psychiatric Association, DSM-5 Task Force. (2013). Diagnostic and statistical manual of mental disorders: DSM-5™ (5th ed.). American Psychiatric Publishing, Inc. https://doi.org/10.1176/appi.books.9780890425596

Anastopoulos, A. D., DuPaul, G. J., Weyandt, L. L., Morrissey-Kane, E., Sommer, J. L., Rhoads, L. H., ... & Gudmundsdottir, B. G. (2018). Rates and patterns of comorbidity among first-year college students with ADHD. Journal of Clinical Child & Adolescent Psychology, 47(2), 236-247. https://doi.org/10.1080/15374416.2015.1105137

Anckarsäter, H., Stahlberg, O., Larson, T., Hakansson, C., Jutblad, S. B., Niklasson, L., ... & Rastam, M. (2006). The impact of ADHD and autism spectrum disorders on temperament, character, and personality development. American Journal of Psychiatry, 163(7), 1239-1244. https://doi.org/10.1176/ajp.2006.163.7.1239

Anker, E., Bendiksen, B., & Heir, T. (2018). Comorbid psychiatric disorders in a clinical sample of adults with ADHD, and associations with education, work, and social characteristics: a cross-sectional study. BMJ open,8(3), e019700. https://doi.org/10.1136/bmjopen-2017-019700

Antshel, K. M. (2008). Attention‐Deficit Hyperactivity Disorder in the context of a high intellectual quotient/giftedness.Developmental Disabilities Research Reviews, 14(4), 293-299. https://doi.org/10.1002/ddrr.34

Antshel, K. M., & Barkley, R. (2009). Developmental and behavioral disorders have grown: attention deficit hyperactivity disorder. Journal of Developmental & Behavioral Pediatrics, 30(1), 81-90. https://doi.org/10.1097/DBP.0b013e31819359ea

Antshel, K. M., Faraone, S. V., Maglione, K., Doyle, A., Fried, R., Seidman, L., & Biederman, J. (2009). Is adult attention-deficit/hyperactivity disorder a valid diagnosis in the presence of high IQ? Psychological Medicine, 39(8), 1325-1335. https://doi.org/10.1017/S0033291708004959

Arnold, L. E., Hodgkins, P., Kahle, J., Madhoo, M., & Kewley, G. (2020). Long-term outcomes of ADHD: Academic Achievement and Performance. Journal of Attention Disorders, 24(1), 73-85. https://doi.org/10.1177/1087054714566076

Arns, M., Heinrich, H., & Strehl, U. (2014). Evaluation of neurofeedback in ADHD: the long and winding road. Biological psychology, 95, 108-115. https://doi.org/10.1016/j.biopsycho.2013.11.013

Asherson, P., Akehurst, R., Kooij, J. S., Huss, M., Beusterien, K., Sasané, R., ... & Hodgkins, P. (2012). Underdiagnosis of adult ADHD: cultural influences and societal burden.Journal of Attention Disorders,16(5_suppl), 20S-38S. https://doi.org/10.1177/1087054711435360

Asherson, P., Young, A. H., Eich-Höchli, D., Moran, P., Porsdal, V., & Deberdt, W. (2014). Differential diagnosis, comorbidity, and treatment of attention-deficit/hyperactivity disorder in relation to bipolar disorder or borderline personality disorder in adults.Current medical research and opinion, 30(8), 1657-1672. https://doi.org/10.1185/03007995.2014.915800

Ayano, G., Tsegay, L., Gizachew, Y., Necho, M., Yohannes, K., Abraha, M., ... & Alati, R. (2023). Corrigendum to ‘Prevalence of attention deficit hyperactivity disorder in adults: Umbrella review of evidence generated across the globe’ [Psychiatry Research 328 (2023) 115449]. Psychiatry Research, 330, 115578. https://doi.org/10.1016/j.psychres.2023.115578

Bangma, D. F., Koerts, J., Fuermaier, A., Mette, C., Zimmermann, M., Toussaint, A. K., ... & Tucha, O. (2019). Financial decision-making in adults with ADHD. Neuropsychology, 33(8), 1065. https://doi.org/10.1037/neu0000571

Beaton, D. M., Sirois, F., & Milne, E. (2022). The role of self‐compassion in the mental health of adults with ADHD. Journal of Clinical Psychology, 78(12), 2497-2512. https://doi.org/10.1002/jclp.23354

Billstedt, E., Gillberg, C., & Gillberg, C. (2005). Autism after adolescence: population-based 13-to 22-year follow-up study of 120 individuals with autism diagnosed in childhood.Journal of autism and developmental disorders, 35(3), 351-360. https://doi.org/10.1007/s10803-005-3302-5

Boomsma, D. I., Saviouk, V., Hottenga, J. J., Distel, M. A., de Moor, M. H., Vink, J. M., ... & Willemsen, G. (2010). Genetic epidemiology of attention deficit hyperactivity disorder (ADHD index) in adults. PloS one, 5(5), e10621. https://doi.org/10.1371/journal.pone.0010621

Choi, W. S., Woo, Y. S., Wang, S. M., Lim, H. K., & Bahk, W. M. (2022). The prevalence of psychiatric comorbidities in adult ADHD compared with non-ADHD populations: A systematic literature review. PloS one, 17(11), e0277175. https://doi.org/10.1371/journal.pone.0277175

Chung, W., Jiang, S. F., Paksarian, D., Nikolaidis, A., Castellanos, F. X., Merikangas, K. R., & Milham, M. P. (2019). Trends in the prevalence and incidence of attention-deficit/hyperactivity disorder among adults and children of different racial and ethnic groups.JAMA Network Open, 2(11), e1914344-e1914344. https://doi.org/10.1001/jamanetworkopen.2019.14344

Del Campo, N., Chamberlain, S. R., Sahakian, B. J., & Robbins, T. W. (2011). The roles of dopamine and noradrenaline in the pathophysiology and treatment of attention-deficit/hyperactivity disorder. Biological psychiatry, 69(12), e145-e157. https://doi.org/10.1016/j.biopsych.2011.02.036

Ditrich, I., Philipsen, A., & Matthies, S. (2021). Borderline personality disorder (BPD) and attention deficit hyperactivity disorder (ADHD) revisited–a review-update on common grounds and subtle distinctions. Borderline personality disorder and emotion dysregulation,8(1), 22. https://doi.org/10.1186/s40479-021-00162-w

Duarte, M., Blay, M., Hasler, R., Pham, E., Nicastro, R., Jan, M., ... & Perroud, N. (2024). Adult ADHD and pathological narcissism: A retrospective analysis. Journal of Psychiatric Research, 174, 245-253. https://doi.org/10.1016/j.jpsychires.2024.04.032

Eakin, L., Minde, K., Hechtman, L., Ochs, E., Krane, E., Bouffard, R., ... & Looper, K. (2004). The marital and family functioning of adults with ADHD and their spouses. Journal of Attention Disorders, 8(1), 1-10. https://doi.org/10.1177/108705470400800101

Eisenbarth, H., Alpers, G. W., Conzelmann, A., Jacob, C. P., Weyers, P., & Pauli, P. (2008). Psychopathic traits in adult ADHD patients. Personality and Individual Differences, 45(6), 468-472. https://doi.org/10.1016/j.paid.2008.05.022

Ersoy, M. A., & Topçu Ersoy, H. (2019). Gender-role attitudes mediate the effects of adult ADHD on marriage and relationships.Journal of Attention Disorders,23(1), 40-50. https://doi.org/10.1177/1087054715618789

Faraone, S. V., & Wilens, T. E. (2007). Effect of stimulant medications for attention-deficit/hyperactivity disorder on later substance use and the potential for stimulant misuse, abuse, and diversion. Journal of Clinical Psychiatry, 68, 15. https://doi.org/10.4088/JCP.1107e28

Faraone, S. V., Biederman, J., Spencer, T., Mick, E., Murray, K., Petty, C., ... & Monuteaux, M. C. (2006). Diagnosing adult attention deficit hyperactivity disorder: are late onset and subthreshold diagnoses valid?. American Journal of Psychiatry, 163(10), 1720-1729. https://doi.org/10.1176/ajp.2006.163.10.1720

Faraone, S. V., Bonvicini, C., & Scassellati, C. (2014). Biomarkers in the Diagnosis of ADHD: Promising Directions. Current Psychiatry Reports, 16(11), 497. https://doi.org/10.1007/s11920-014-0497-1

Fleming, A. P., McMahon, R. J., Moran, L. R., Peterson, A. P., & Dreessen, A. (2015). Pilot randomized controlled trial of dialectical behavior therapy group skills training for ADHD among college students. Journal of Attention Disorders, 19(3), 260-271. https://doi.org/10.1177/1087054714535951

Flory, K., Molina, B. S., Pelham, Jr, W. E., Gnagy, E., & Smith, B. (2006). Childhood ADHD predicts risky sexual behavior in young adulthood. Journal of clinical child and adolescent psychology, 35(4), 571-577. https://doi.org/10.1207/s15374424jccp3504_8

Franke, B., Michelini, G., Asherson, P., Banaschewski, T., Bilbow, A., Buitelaar, J. K., ... & Reif, A. (2018). Live fast, die young? A review of the developmental trajectories of ADHD across the lifespan. European neuropsychopharmacology, 28(10), 1059-1088. https://doi.org/10.1016/j.euroneuro.2018.08.001

Fuermaier, A. B., Tucha, L., Butzbach, M., Weisbrod, M., Aschenbrenner, S., & Tucha, O. (2021). ADHD at the workplace: ADHD symptoms, diagnostic status, and work-related functioning. Journal of Neural Transmission, 128(7), 1021-1031. https://doi.org/10.1007/s00702-021-02309-z

Fuermaier, A. B., Tucha, L., Evans, B. L., Koerts, J., de Waard, D., Brookhuis, K., ... & Tucha, O. (2017). Driving and attention deficit hyperactivity disorder. Journal of neural transmission, 124(Suppl 1), 55-67. https://doi.org/10.1007/s00702-015-1465-6

Gentile, J. P., Atiq, R., & Gillig, P. M. (2006). Adult ADHD: diagnosis, differential diagnosis, and medication management. Psychiatry (Edgmont), 3(8), 25.

Giannakopoulos, G. (2025). Adolescents with ADHD in the school environment: A comprehensive review of academic, social, and emotional challenges and interventions. J. Clin. Images Med. Case Rep, 6, 3528. https://doi.org/10.52768/2766-7820/3528

Ginsberg, Y., Quintero, J., Anand, E., Casillas, M., & Upadhyaya, H. P. (2014). Underdiagnosis of attention-deficit/hyperactivity disorder in adult patients: a review of the literature. Prim Care Companion CNS Disord, 16(3), 1-8. https://doi.org/10.4088/PCC.13r01600

Gordon, C. T., & Fabiano, G. A. (2019). The Transition of Youth with ADHD into the Workforce: A Review and Future Directions. Clinical child and family psychology review, 22(3), 316-347. https://doi.org/10.1007/s10567-019-00274-4

Harpin, V., Mazzone, L., Raynaud, J. P., Kahle, J., & Hodgkins, P. (2016). Long-term outcomes of ADHD: a systematic review of self-esteem and social function. Journal of Attention Disorders, 20(4), 295-305. https://doi.org/10.1177/1087054713486516

Hesslinger, B., Tebartz van Elst, L., Nyberg, E., Dykierek, P., Richter, H., Berner, M., & Ebert, D. (2002). Psychotherapy of attention deficit hyperactivity disorder in adults: A pilot study using a structured skills training program. European Archives of Psychiatry and Clinical Neuroscience, 252(4), 177-184. https://doi.org/10.1007/s00406-002-0379-0

Hirvikoski, T., Lindström, T., Carlsson, J., Waaler, E., Jokinen, J., & Bölte, S. (2017). Psychoeducational groups for adults with ADHD and their significant others (PEGASUS): A pragmatic multicenter and randomized controlled trial. European Psychiatry, 44, 141-152. https://doi.org/10.1016/j.eurpsy.2017.04.005

Hirvikoski, T., Waaler, E., Alfredsson, J., Pihlgren, C., Holmström, A., Johnson, A., ... & Nordström, A. L. (2011). Reduced ADHD symptoms in adults with ADHD after structured skills training group: results from a randomized controlled trial. Behaviour Research and Therapy, 49(3), 175-185. https://doi.org/10.1016/j.brat.2011.01.001

Holden, S. E., Jenkins-Jones, S., Poole, C. D., Morgan, C. L., Coghill, D., & Currie, C. J. (2013). The prevalence and incidence, resource use, and financial costs of treating people with attention deficit/hyperactivity disorder (ADHD) in the United Kingdom (1998 to 2010). Child and adolescent psychiatry and mental health, 7(1), 34. https://doi.org/10.1186/1753-2000-7-34

Holst, Y., & Thorell, L. B. (2020). Functional impairments among adults with ADHD: A comparison with adults with other psychiatric disorders and links to executive deficits. Applied Neuropsychology: Adult. https://doi.org/10.1080/23279095.2018.1532429

Hosain, G. M., Berenson, A. B., Tennen, H., Bauer, L. O., & Wu, Z. H. (2012). Attention deficit hyperactivity symptoms and risky sexual behavior in young adult women.Journal of Women's Health, 21(4), 463-468. https://doi.org/10.1089/jwh.2011.2825

Instanes, J. T., Klungsøyr, K., Halmøy, A., Fasmer, O. B., & Haavik, J. (2018). Adult ADHD and comorbid somatic disease: a systematic literature review. Journal of Attention Disorders,22(3), 203-228. https://doi.org/10.1177/1087054716669589

Jensen, C. M., Amdisen, B. L., Jørgensen, K. J., & Arnfred, S. M. (2016). Cognitive behavioural therapy for ADHD in adults: systematic review and meta-analyses. ADHD Attention Deficit and Hyperactivity Disorders, 8(1), 3-11. https://doi.org/10.1007/s12402-016-0188-3

Joseph, A., Kosmas, C. E., Patel, C., Doll, H., & Asherson, P. (2019). Health-related quality of life and work productivity of adults with ADHD: a UK web-based cross-sectional survey. Journal of Attention Disorders, 23(13), 1610-1623. https://doi.org/10.1177/1087054718799367

Katzman, M. A., Bilkey, T. S., Chokka, P. R., Fallu, A., & Klassen, L. J. (2017). Adult ADHD and comorbid disorders: clinical implications of a dimensional approach. BMC psychiatry, 17(1), 302. https://doi.org/10.1186/s12888-017-1463-3

Kessler, R. C., Adler, L., Barkley, R., Biederman, J., Conners, C. K., Demler, O., ... & Zaslavsky, A. M. (2006). The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication. American Journal of Psychiatry, 163(4), 716-723. https://doi.org/10.1176/ajp.2006.163.4.716

Knouse, L. E., Teller, J., & Brooks, M. A. (2017). Meta-analysis of cognitive–behavioral treatments for adult ADHD. Journal of consulting and clinical psychology, 85(7), 737. https://doi.org/10.1037/ccp0000216

Koisaari, T., Michelsson, K., Holopainen, J. M., Maksimainen, R., Päivänsalo, J., Rantala, K., & Tervo, T. (2015). Traffic and criminal behavior of adults with attention deficit–hyperactivity with a prospective follow-up from birth to the age of 40 years. Traffic Injury Prevention, 16(8), 824-830. https://doi.org/10.1080/15389588.2015.1029068

Kooij, J.J.S. (2022). Diagnostics. In: Adult ADHD. Springer, Cham. https://doi.org/10.1007/978-3-030-82812-7

Koyuncu, A., Ayan, T., İnce Guliyev, E., Erbilgin, S., & Deveci, E. (2022). ADHD and anxiety disorder comorbidity in children and adults: Diagnostic and therapeutic challenges. Current Psychiatry Reports, 24(2), 129-140. https://doi.org/10.1007/s11920-022-01324-5

Lai MC, Lombardo MV, Baron-Cohen S. Autism. Lancet. 2014 Mar 8; 383(9920): 896-910. PMID: 24074734. https://doi.org/10.1016/S0140-6736(13)61539-1

Landes, S. D., & London, A. S. (2021). Self-reported ADHD and adult health in the United States. Journal of Attention Disorders, 25(1), 3-13. https://doi.org/10.1177/1087054718757648

Larsson, H., Chang, Z., D'Onofrio, B. M., & Lichtenstein, P. (2014). The heritability of clinically diagnosed attention-deficit/hyperactivity disorder across the lifespan. Psychological medicine, 44(10), 2223-2229. https://doi.org/10.1017/S0033291713002493

Lasky, A. K., Weisner, T. S., Jensen, P. S., Hinshaw, S. P., Hechtman, L., Arnold, L. E., ... & Swanson, J. M. (2016). ADHD in context: Young adults’ reports of the impact of occupational environment on the manifestation of ADHD. Social Science & Medicine, 161, 160-168. https://doi.org/10.1016/j.socscimed.2016.06.003

Lee, S. S., Lahey, B. B., Owens, E. B., & Hinshaw, S. P. (2008). Few preschool boys and girls with ADHD are well-adjusted during adolescence. Journal of Abnormal Child Psychology, 36(3), 373-383. https://doi.org/10.1007/s10802-007-9184-6

Leppert, B., Riglin, L., Wootton, R. E., Dardani, C., Thapar, A., Staley, J. R., ... & Stergiakouli, E. (2021). The effect of attention deficit/hyperactivity disorder on physical health outcomes: a 2-sample Mendelian randomization study. American Journal of Epidemiology, 190(6), 1047-1055. https://doi.org/10.1093/aje/kwaa273

Linehan, M. M. (1993). Dialectical behavior therapy for treatment of borderline personality disorder: implications for the treatment of substance abuse.NIDA research monograph, 137, 201-201. https://doi.org/10.1037/e495912006-012

London, A. S., & Landes, S. D. (2016). Attention deficit hyperactivity disorder and adult mortality. Preventive medicine, 90, 8-10. https://doi.org/10.1016/j.ypmed.2016.06.021

London, A. S., & Landes, S. D. (2022). Attention Deficit Hyperactivity Disorder and the Age Pattern of Adult Mortality. Biodemography and social biology, 67(1), 28-39. https://doi.org/10.1080/19485565.2021.2020618

López-Pinar, C., Martínez-Sanchis, S., Carbonell-Vaya, E., Fenollar-Cortés, J., & Sánchez-Meca, J. (2018). Long-term efficacy of psychosocial treatments for adults with attention-deficit/hyperactivity disorder: a meta-analytic review.Frontiers in psychology,9, 638. https://doi.org/10.3389/fpsyg.2018.00638

Mariani, J. J., Khantzian, E. J., & Levin, F. R. (2014). The self‐medication hypothesis and psychostimulant treatment of cocaine dependence: an update. The American journal on addictions, 23(2), 189-193. https://doi.org/10.1111/j.1521-0391.2013.12086.x

McKee, T. E. (2017). Peer relationships in undergraduates with ADHD symptomatology: Selection and quality of friendships.Journal of Attention Disorders,21(12), 1020-1029. https://doi.org/10.1177/1087054714554934

Merkel Jr, R. L., Nichols, J. Q., Fellers, J. C., Hidalgo, P., Martinez, L. A., Putziger, I., ... & Cox, D. J. (2016). Comparison of on-road driving between young adults with and without ADHD. Journal of Attention Disorders, 20(3), 260-269. https://doi.org/10.1177/1087054712473832

Milioni, A. L. V., Chaim, T. M., Cavallet, M., de Oliveira, N. M., Annes, M., dos Santos, B., ... & Cunha, P. J. (2017). High IQ may “mask” the diagnosis of ADHD by compensating for deficits in executive functions in treatment-naïve adults with ADHD. Journal of Attention Disorders, 21(6), 455-464. https://doi.org/10.1177/1087054714554933

Millon T. (1997). Millon Clinical Multiaxial Inventory-III manual (2nd ed.). National Computer Systems, Minneapolis, MN.

Millon, T., & Davis, R. (1997). Millon Clinical Multiaxial Inventory-III [manual, second edition]. Bloomington, MN: Pearson Assessments.

Mitchell, J. T., McIntyre, E. M., English, J. S., Dennis, M. F., Beckham, J. C., & Kollins, S. H. (2017). A pilot trial of mindfulness meditation training for ADHD in adulthood: Impact on core symptoms, executive functioning, and emotion dysregulation. Journal of Attention Disorders, 21(13), 1105-1120. https://doi.org/10.1177/1087054713513328

Monastra, V. J., Lynn, S., Linden, M., Lubar, J. F., Gruzelier, J., & La Vaque, T. J. (2006). Electroencephalographic biofeedback in the treatment of attention-deficit/hyperactivity disorder. Journal of Neurotherapy, 9(4), 5-34. https://doi.org/10.1300/J184v09n04_02

Neff, K. (2003a). Self‐compassion: An alternative conceptualization of a healthy attitude toward oneself. Self and Identity, 2(2), 85-101. https://doi.org/10.1080/15298860309032

Neff, K. (2003b). The development and validation of a scale to measure self‐compassion. Self and Identity, 2(3), 223-250. https://doi.org/10.1080/15298860309027

Nelson, J. M., & Liebel, S. W. (2018). Anxiety and depression among college students with attention-deficit/hyperactivity disorder (ADHD): Cross-informant, sex, and subtype differences. Journal of American College Health, 66(2), 123-132. https://doi.org/10.1080/07448481.2017.1382499

Newark, P. E., Elsässer, M., & Stieglitz, R. D. (2016). Self-esteem, self-efficacy, and resources in adults with ADHD. Journal of Attention Disorders, 20(3), 279-290. https://doi.org/10.1177/1087054712459561

Nierenberg, A. A., Miyahara, S., Spencer, T., Wisniewski, S. R., Otto, M. W., Simon, N., ... & STEP-BD Investigators. (2005). Clinical and diagnostic implications of lifetime attention-deficit/hyperactivity disorder comorbidity in adults with bipolar disorder: data from the first 1000 STEP-BD participants. Biological psychiatry, 57(11), 1467-1473. https://doi.org/10.1016/j.biopsych.2005.01.036

Nikolas, M. A., & Burt, S. A. (2010). Genetic and environmental influences on ADHD symptom dimensions of inattention and hyperactivity: a meta-analysis. Journal of Abnormal Psychology, 119(1), 1. https://doi.org/10.1037/a0018010

Oroian, B. A., Costandache, G., Popescu, E., Nechita, P., & Szalontay, A. (2024). Comparative analysis of self-stimulatory behaviors in ASD and ADHD. European Psychiatry, 67(S1), S220-S220. https://doi.org/10.1192/j.eurpsy.2024.471

Pan, M. R., Zhang, S. Y., Qiu, S. W., Liu, L., Li, H. M., Zhao, M. J., ... & Qian, Q. J. (2022). Efficacy of cognitive behavioural therapy in medicated adults with attention-deficit/hyperactivity disorder in multiple dimensions: a randomised controlled trial. European Archives of Psychiatry and Clinical Neuroscience, 272(2), 235-255. https://doi.org/10.1007/s00406-021-01236-0

Paulson, J. F., Buermeyer, C., & Nelson-Gray, R. O. (2005). Social rejection and ADHD in young adults: An analogue experiment. Journal of Attention Disorders, 8(3), 127-135. https://doi.org/10.1177/1087054705277203

Philipsen, A., Graf, E., Tebartz van Elst, L., Jans, T., Warnke, A., Hesslinger, B., ... & Berger, M. (2010). Evaluation of the efficacy and effectiveness of a structured disorder-tailored psychotherapy in ADHD in adults: study protocol of a randomized controlled multicentre trial. ADHD Attention Deficit and Hyperactivity Disorders, 2(4), 203-212. https://doi.org/10.1007/s12402-010-0046-7

Pingault, J. B., Viding, E., Galéra, C., Greven, C. U., Zheng, Y., Plomin, R., & Rijsdijk, F. (2015). Genetic and environmental influences on the developmental course of attention-deficit/hyperactivity disorder symptoms from childhood to adolescence. JAMA psychiatry, 72(7), 651-658. https://doi.org/10.1001/jamapsychiatry.2015.0469

Post, R. E., & Kurlansik, S. L. (2012). Diagnosis and management of attention-deficit/hyperactivity disorder in adults. American Family Physician, 85(9), 890-896.

Quenneville, A. F., Kalogeropoulou, E., Nicastro, R., Weibel, S., Chanut, F., & Perroud, N. (2022). Anxiety disorders in adult ADHD: A frequent comorbidity and a risk factor for externalizing problems. Psychiatry research, 310, 114423. https://doi.org/10.1016/j.psychres.2022.114423

Raman, S. R., Man, K. K., Bahmanyar, S., Berard, A., Bilder, S., Boukhris, T., ... & Wong, I. C. (2018). Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases. The Lancet Psychiatry, 5(10), 824-835. https://doi.org/10.1016/S2215-0366(18)30293-1

Randell, N. J., Charlton, S. G., & Starkey, N. J. (2020). Driving with ADHD: Performance Effects and Environmental Demands in Traffic. Journal of Attention Disorders, 24(11), 1570-1580. https://doi.org/10.1177/1087054716658126

Reale, L., & Bonati, M. (2018). ADHD prevalence estimates in Italian children and adolescents: a methodological issue. Italian Journal of Pediatrics, 44(1), 108. https://doi.org/10.1186/s13052-018-0545-2

Retz, W. (2020). Attention deficit hyperactivity disorder and psychopathy in adults. The Wiley International Handbook on Psychopathic Disorders and the Law, 533-544. https://doi.org/10.1002/9781119159322.ch23

Retz, W., Stieglitz, R. D., Corbisiero, S., Retz-Junginger, P., & Roesler, M. (2012). Emotional dysregulation in adult ADHD: what is the empirical evidence?. Expert review of neurotherapeutics, 12(10), 1241-1251. https://doi.org/10.1586/ern.12.109

Rong, Ying, Chang-Jiang Yang, Ye Jin, and Yue Wang. "Prevalence of attention-deficit/hyperactivity disorder in individuals with autism spectrum disorder: A meta-analysis." Research in Autism Spectrum Disorders, 83 (2021): 101759. https://doi.org/10.1016/j.rasd.2021.101759

Rooney, M., Chronis-Tuscano, A., & Yoon, Y. (2012). Substance use in college students with ADHD. Journal of Attention Disorders, 16(3), 221-234. https://doi.org/10.1177/1087054710392536

Sacchetti, G. M., & Lefler, E. K. (2017). ADHD symptomology and social functioning in college students. Journal of Attention Disorders, 21(12), 1009-1019. https://doi.org/10.1177/1087054714557355

Safren, S. A., Otto, M. W., Sprich, S., Winett, C. L., Wilens, T. E., & Biederman, J. (2005). Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms.Behaviour Research and Therapy, 43(7), 831-842. https://doi.org/10.1016/j.brat.2004.07.001

Salari, N., Ghasemi, H., Abdoli, N., Rahmani, A., Shiri, M. H., Hashemian, A. H., ... & Mohammadi, M. (2023). The global prevalence of ADHD in children and adolescents: a systematic review and meta-analysis. Italian Journal of Pediatrics, 49(1), 48. https://doi.org/10.1186/s13052-023-01456-1

Saviouk, V., Hottenga, J. J., Slagboom, E. P., Distel, M. A., de Geus, E. J., Willemsen, G., & Boomsma, D. I. (2011). ADHD in Dutch adults: heritability and linkage study.American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 156(3), 352-362. https://doi.org/10.1002/ajmg.b.31170

Schiweck, C., Arteaga-Henriquez, G., Aichholzer, M., Thanarajah, S. E., Vargas-Cáceres, S., Matura, S., ... & Reif, A. (2021). Comorbidity of ADHD and adult bipolar disorder: A systematic review and meta-analysis. Neuroscience & biobehavioral reviews, 124, 100-123. https://doi.org/10.1016/j.neubiorev.2021.01.017

Shoham, R., Sonuga-Barke, E., Yaniv, I., & Pollak, Y. (2021). What drives risky behavior in ADHD: insensitivity to its risk or fascination with its potential benefits?. Journal of Attention Disorders, 25(14), 1988-2002. https://doi.org/10.1177/1087054720950820

Sibley, M. H., Mitchell, J. T., & Becker, S. P. (2016). Method of adult diagnosis influences estimated persistence of childhood ADHD: a systematic review of longitudinal studies. The Lancet Psychiatry, 3(12), 1157-1165. https://doi.org/10.1016/S2215-0366(16)30190-0

Simon, V., Czobor, P., Bálint, S., Mészáros, A., & Bitter, I. (2009). Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis. The British Journal of Psychiatry, 194(3), 204-211. https://doi.org/10.1192/bjp.bp.107.048827

Song, P., Zha, M., Yang, Q., Zhang, Y., Li, X., & Rudan, I. (2021). The prevalence of adult attention-deficit hyperactivity disorder: A global systematic review and meta-analysis.Journal of Global Health,11, 04009. https://doi.org/10.7189/jogh.11.04009

Stern, A., Pollak, Y., Bonne, O., Malik, E., & Maeir, A. (2017). The relationship between executive functions and quality of life in adults with ADHD.Journal of Attention Disorders, 21(4), 323-330. https://doi.org/10.1177/1087054713504133

Stickley, A., Koyanagi, A., Takahashi, H., Ruchkin, V., & Kamio, Y. (2017). Attention-deficit/hyperactivity disorder symptoms and loneliness among adults in the general population. Research in Developmental Disabilities, 62, 115-123. https://doi.org/10.1016/j.ridd.2017.01.007

Storebø, O. J., & Simonsen, E. (2016). The association between ADHD and antisocial personality disorder (ASPD): a review. Journal of Attention Disorders, 20(10), 815-824. https://doi.org/10.1177/1087054713512150

Tamam, L., Karakus, G., & Ozpoyraz, N. (2008). Comorbidity of adult attention-deficit hyperactivity disorder and bipolar disorder: prevalence and clinical correlates. European Archives of Psychiatry and Clinical Neuroscience, 258(7), 385-393. https://doi.org/10.1007/s00406-008-0807-x

Theule, J., Hurl, K. E., Cheung, K., Ward, M., & Henrikson, B. (2019). Exploring the relationships between problem gambling and ADHD: A meta-analysis.Journal of Attention Disorders, 23(12), 1427-1437. https://doi.org/10.1177/1087054715626512

Torgersen, T., Gjervan, B., & Rasmussen, K. (2006). ADHD in adults: a study of clinical characteristics, impairment and comorbidity. Nordic journal of psychiatry, 60(1), 38-43. https://doi.org/10.1080/08039480500520665

Townes, P., Liu, C., Panesar, P., Devoe, D., Lee, S. Y., Taylor, G., ... & Schachar, R. (2023). Do ASD and ADHD have distinct executive function deficits? A systematic review and meta-analysis of direct comparison studies. Journal of Attention Disorders, 27(14), 1571-1582. https://doi.org/10.1177/10870547231190494

Vaag, J. R., Lara-Cabrera, M. L., Hjemdal, O., Gjervan, B., & Torgersen, T. (2019). Psychoeducational groups versus waitlist in treatment of attention-deficit hyperactivity/impulsivity disorder (ADHD) in adults: a protocol for a pilot randomized waitlist-controlled multicenter trial. Pilot and Feasibility Studies, 5(1), 17. https://doi.org/10.1186/s40814-019-0401-1

Vidal, R., Bosch, R., Nogueira, M., Gómez-Barros, N., Valero, S., Palomar, G., ... & Ramos-Quiroga, J. A. (2013). Psychoeducation for adults with attention deficit hyperactivity disorder vs. cognitive behavioral group therapy: a randomized controlled pilot study. The Journal of nervous and mental disease, 201(10), 894-900. https://doi.org/10.1097/NMD.0b013e3182a5c2c5

Volkow, N. D., Wang, G. J., Kollins, S. H., Wigal, T. L., Newcorn, J. H., Telang, F., ... & Swanson, J. M. (2009). Evaluating dopamine reward pathway in ADHD: clinical implications. Jama, 302(10), 1084-1091. https://doi.org/10.1001/jama.2009.1308

Vos, M., & Hartman, C. A. (2022). The decreasing prevalence of ADHD across the adult lifespan is confirmed (Journal of Global Health, 12, 03024). https://doi.org/10.7189/jogh.12.03024

Webster, N. (2018). ADHD in adulthood: A qualitative study of lived experience, self-esteem, diagnosis and service provision in the UK.Published online.

Weiner, L., Perroud, N., & Weibel, S. (2019). Attention deficit hyperactivity disorder and borderline personality disorder in adults: a review of their links and risks. Neuropsychiatric disease and treatment, 3115-3129. https://doi.org/10.2147/NDT.S192871

Weiss, M., Murray, C., Wasdell, M., Greenfield, B., Giles, L., & Hechtman, L. (2012). A randomized controlled trial of CBT therapy for adults with ADHD with and without medication. BMC psychiatry, 12(1), 30. https://doi.org/10.1186/1471-244X-12-30

Weyandt, L., DuPaul, G. J., Verdi, G., Rossi, J. S., Swentosky, A. J., Vilardo, B. S., ... & Carson, K. S. (2013). The performance of college students with and without ADHD: Neuropsychological, academic, and psychosocial functioning. Journal of Psychopathology and Behavioral Assessment, 35(4), 421-435. https://doi.org/10.1007/s10862-013-9351-8

Wymbs, B. T., Canu, W. H., Sacchetti, G. M., & Ranson, L. M. (2021). Adult ADHD and romantic relationships: What we know and what we can do to help. Journal of Marital and Family Therapy, 47(3), 664-681. https://doi.org/10.1111/jmft.12475

Zylowska, L., Ackerman, D. L., Yang, M. H., Futrell, J. L., Horton, N. L., Hale, T. S., ... & Smalley, S. L. (2008). Mindfulness meditation training in adults and adolescents with ADHD: A feasibility study. Journal of Attention Disorders, 11(6), 737-746. https://doi.org/10.1177/1087054707308502

Downloads

Published

2025-12-02

How to Cite

Bertolucci, I. . (2025). Attention Deficit Hyperactivity Disorder in Adulthood: A Comprehensive. Journal of Psychology and Psychotherapy Research, 12, 16–28. https://doi.org/10.12974/2313-1047.2025.12.03

Issue

Section

Articles