3D Printing of Hydrogel/BaTiO3 Composite Scaffolds with Highly Improved Mechanical, Electrical, and Degradable Properties

Authors

  • Yue Zhang "State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China" & "Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China"
  • Jinhan He "State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China" & "Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China"
  • Jin Su "State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China" & "Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China"
  • Annan Chen "Centre for Advanced Structural Materials, Department of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China" & "Centre for Advanced Structural Materials, City University of Hong Kong Shenzhen Research Institute, Greater Bay Joint Division, Shenyang National Laboratory for Materials Science, Shenzhen 518057, China"
  • Yinjin Li "State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China" & "Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China"
  • Yifei Li "State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China" & "Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China"
  • Chunze Yan "State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China" & "Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China"
  • Yusheng Shi "State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China" & "Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China"

DOI:

https://doi.org/10.12974/2311-8717.2023.11.07

Keywords:

3D printing, Hydrogel/BaTiO3 scaffold, Machinal property, Electrical property, Degradability

Abstract

In clinical practice, the restoration of cartilage injury is a tough task. And manufacturing degradable cartilage scaffolds with strong mechanical properties and electrical activity remains a significant issue. In this study, the hydrogel/BaTiO3 composite scaffolds with greatly improved mechanical, electrical, and degradable properties were formed by digital light processing 3D printing. We found that the addition of BaTiO3 powders enabled the significant improvement of the compressive strength (212.8 kPa) and energy absorption (32.0 mJ/m3), which were as three and six times as those of pure hydrogel scaffolds, respectively. Besides, the composite scaffolds showed a voltage output of above 100 mV, which was two orders of magnitude higher than that of pure hydrogel scaffolds. This voltage output allows for the simulation of electrical microenvironment in native tissues that promote cartilage regeneration and remodeling. Finally, the degradation rate of the composite scaffolds reached 7.1% after 14 days of simulated body fluid (SBF) immersion, while that of the pure hydrogel scaffolds was only 2.8%. This study provides insight into the fabrication of high-performance functional scaffolds for treating cartilage defect.

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Published

2023-12-27

How to Cite

Zhang, Y. ., He, J. ., Su, J. ., Chen, A. ., Li, Y. ., Li, Y. ., Yan, C. ., & Shi, Y. . (2023). 3D Printing of Hydrogel/BaTiO3 Composite Scaffolds with Highly Improved Mechanical, Electrical, and Degradable Properties. Journal of Composites and Biodegradable Polymers, 11, 49–58. https://doi.org/10.12974/2311-8717.2023.11.07

Issue

Vol. 11 (2023)

Section

Articles