Hypothalamic Revascularization and Rejuvenation
DOI:
https://doi.org/10.12974/2309-6128.2014.02.01.4Keywords:
Aging, Arcuate nucleus, Hypothalamic ischemia, Omental transplantation.Abstract
Background: Since 1990 and to date, four therapeutic methods have been used against aging. All of them, to increase the plasma growth hormone levels.
Material and Method: We choose 38 patients to analyse the postoperative rejuvenation. Previously, all of them have been received omental transplantation on the optic chiasma, the carotid bifurcation and the anterior perforated space. Patients with stroke in 14 cases, Alzheimer´s disease (AD) in 23 and Huntington´s disease (HD) in 1. The clinical data of rejuvenation were obtained by observation, videotape and photography.
Results: Neurological improvement in patients with stroke, AD and HD were better during the first weeks after surgery than in the following months or years. Besides this, between 1 to 4 months after surgery, 32 patients (84.21%) showed rejuvenation and in the rest, there were not changes. These 6 last patients presented dilation of the third ventricle.
Conclusions: These results indicate that the primary cause of aging is of ischemic origin, in the arcuate nucleus of the hypothalamus. Because, in contrast to this, its revascularization by means of omental tissue produce rejuvenation. Therefore, our surgical method improve the function of the residual arcuate nucleus and adjacent zones.
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